Perils of Perimenopause

The Gajer Practice Blogs

July 31, 2024

Are you a woman between the ages of 35-55 who has noticed that she doesn’t feel or perform as well as she used to? We rarely talk about the period in a woman’s life where she experiences symptoms of perimenopause. For some women, this is a short period of time right around age 50; for others, it is a long, drawn-out period of many years where things don’t feel quite right.

The symptoms of perimenopause include irregular periods, hot flashes, night sweats, sleep problems, mood changes, vaginal dryness, decreased libido, urinary changes, weight gain, breast tenderness, dry skin, thinning hair, and memory problems. That’s quite a list!

Today, we will explore what is happening during this time period and what can be done to help you be your best during this sometimes tumultuous time.

Perimenopause is defined as the transitional period before menopause when a woman’s body undergoes hormonal changes, leading to various physical and emotional symptoms. Despite the significance of hormone balance, conventional medicine often pays little attention to this aspect of women’s health unless addressing pregnancy or infertility. Recent research suggests that women who understand and manage their hormones throughout their lives tend to perform better and experience overall improved well-being.

As perimenopause ensues, progesterone is the first hormone to decrease.  Progesterone is a calming hormone, and when it is insufficient, women often experience fatigue, sleep problems, anxiety, weight gain, and brain fog.  Progesterone is also anti-inflammatory, and its drop during perimenopause can unmask an autoimmune condition such as arthritis.  Lack of progesterone can also lead to joint and muscle aches.  Progesterone can further be affected by periods of high stress, which are common during the years that women’s hormones begin to change. Progesterone and cortisol share a production pathway, and an increased demand for cortisol during stress can deplete progesterone levels, potentially leading to hormonal imbalances. This imbalance can affect mood, sleep, and overall well-being, highlighting the importance of managing stress and maintaining a healthy lifestyle.

During perimenopause, estradiol levels fluctuate significantly due to the ovaries’ inconsistent production of this hormone. These fluctuations can lead to irregular menstrual cycles and various symptoms, such as hot flashes, mood swings, and sleep disturbances. As perimenopause progresses, the overall trend is a gradual decline in estradiol levels until they stabilize at a lower level post-menopause.

If you are experiencing these symptoms, you are not alone, and you are NOT going crazy.  Dr. Gajer and her team are ready to support you and help you get on a path to living in the healthiest version of your body.

To start your return to balance, you can implement several lifestyle changes to ease the symptoms you may be experiencing.  Focus on a diet rich in minimally processed, whole foods—those found in nature without significant modification. Aim for 3 cups of vegetables daily and at least 70g of high-quality, antibiotic- and hormone-free protein sources. Healthy fats are also crucial during this time, as they support hormone production; include sources like nuts, avocado, and olive oil in your diet.

Balancing hormones during this period through lifestyle changes, nutraceuticals, and/or bioidentical hormones can significantly alleviate or even resolve these issues.

CLICK HERE TO SCHEDULE A CONSULTATION WITH DR. GAJER, Nurse Practitioner SARA GARCIA, or Clinical Director of the Gajer Hormone Program PATRICK GAUTHIER.

We hope to see you soon!

SHARE THIS
Search
RECENT POSTS
RELATED ARTICLES
July 28, 2026

Your Skin Has a Biological Age Too. Here’s How We Invest in It Early

We spend a lot of time in this practice talking about biological age. We measure it, we track it, we work to move it. We optimize hormones, metabolism, muscle, and the quiet inflammatory background that ages a body from the inside.
July 21, 2026

I’m 44 and My Biological Age Is 32. Here’s the Bloodwork Behind It.

My first reaction was not celebration but curiosity. As a physician, I do not trust a good number any more than I trust a bad one until I understand where it came from and what it actually measures.
June 30, 2026

Low-Dose Ketamine Lozenges: A New Frontier in Mental Health Treatment

For most of the modern era, we believed depression was slow to treat by nature. You started a medication, you waited four to six weeks, and you hoped. We told patients this so many times it began to feel like a law of physics: the brain heals slowly, if it heals at all.

Submit a contact form to be contacted by our team!

Special

SUMMER SAVINGS SALE!

25% off Everything in the app.

July 2nd - July 6th, 2026

CODE: SUMMER26

The Peptide Revolution

Reserve your seat now for the 30-Minute Webinar & take the first step toward next-level performance